LTP in Synapse
Forfatter:
Dilawar Singh
Sidst opdateret:
5 år siden
Licens:
Creative Commons CC BY 4.0
Resumé:
Long Term Potentiation (LTP) in synapse.
\begin
Opdag hvorfor 18 millioner mennesker verden rundt stoler på Overleaf med deres arbejde.
Long Term Potentiation (LTP) in synapse.
\begin
Opdag hvorfor 18 millioner mennesker verden rundt stoler på Overleaf med deres arbejde.
% FIGURE shows LTP in spine.
\RequirePackage{luatex85,shellesc}
\documentclass[crop]{standalone}
\usepackage{pgfplots}
\pgfplotsset{compat=1.15}
\usepackage{tikz}
\usetikzlibrary{positioning,calc,shapes,hobby}
\usetikzlibrary{scopes}
\usetikzlibrary{fit}
\usetikzlibrary{intersections, pgfplots.fillbetween}
\usetikzlibrary{arrows}
% Background layer.
\pgfdeclarelayer{bg}
\pgfdeclarelayer{ft}
\pgfsetlayers{bg,main,ft}
\renewcommand{\familydefault}{\sfdefault}
\pgfmathsetseed{10}
\input{structure}
\input{channel}
% Macros
\newcommand\VESICLE[3]{ % name, location, scale
\def\NODESIZE{1}
\begin{scope}[shift={(#2)}]
\node[circle,fill=white, inner sep=#3*\NODESIZE mm] (#1) at (0,0) {};
\foreach \i in {1,...,5} {
\pgfmathsetmacro\x{rand*\NODESIZE}
\pgfmathsetmacro\y{rand*\NODESIZE}
\node[fill=black!50, draw=none,circle,inner sep=0.7pt] at (\x mm,\y mm) {};
}
\end{scope}
}
\begin{document}
\begin{tikzpicture}[hobby]
\SPINEWITHAXON{S1}{(-4,0)}{0.7}
\SPINEWITHAXON{S2}{(4,0)}{1.2}
% Now add some pre-synaptic vesicle
\VESICLE{v1}{[yshift=0.75mm]S1_PRE_R2}{1}
\VESICLE{v2}{[shift=(10:7mm)]v1}{1.2}
\VESICLE{v3}{[shift=(180:4mm)]v1}{1}
\VESICLE{v1}{[yshift=0.75mm]S2_PRE_R2}{1.2}
\VESICLE{v2}{[shift=(20:7mm)]v1}{1.2}
\VESICLE{v3}{[shift=(170:6mm)]v1}{1.2}
\draw[-stealth, black, line width=1mm] (S1) to[] node[above] {\Large LTP} (S2);
\draw[-stealth, gray, dashed, very thick] ([yshift=-4mm]S2.west) to[]
([yshift=-4mm]S1.east);
% ADD RECEPTORS ON POST MEMBRANE.
\CHANNEL{S1_SN1}{0.2}{0.1}{0}{black}{10}
\CHANNEL{S1_SN2}{0.3}{0.2}{40}{blue}{0}
\CHANNEL{S1_SN3}{0.2}{0.1}{30}{black}{-30}
\CHANNEL{S1_SE1}{0.2}{0.1}{0}{black}{-60}
\CHANNEL{S2_SN1}{0.2}{0.1}{0}{black}{10}
\CHANNEL{S2_SN2}{0.3}{0.2}{40}{blue}{0}
\CHANNEL{S2_SN3}{0.2}{0.1}{30}{black}{-30}
\CHANNEL{S2_SE1}{0.2}{0.1}{0}{black}{-60}
\coordinate (x1) at ([shift=(110:4mm)]S2_SE1);
\coordinate (x2) at ([shift=(20:4mm)]S2_SN1);
\coordinate (x3) at ([shift=(0:4mm)]S2_SN2);
\CHANNEL{x1}{0.3}{0.2}{40}{blue}{-60}
\CHANNEL{x2}{0.3}{0.2}{40}{blue}{10}
\CHANNEL{x3}{0.2}{0.1}{0}{black}{-10}
\end{tikzpicture}
\end{document}